Dr. Ting Wang is the inaugural Sanford C. and Karen P. Loewentheil Distinguished Professor of Medicine at Washington University School of Medicine in St. Louis. Dr. Wang studies the genetic and epigenetic impact of transposable element (TE) on gene regulation. His group is known for defining the widespread contribution of TEs to the evolution of species-specific gene regulatory networks as well as to the conservation of 3D genome architecture, and for revealing that epigenetic dysregulation of TEs is a major mechanism driving oncogenesis.
Dr. Wang’s lab investigates epigenetic determinants of cell fates in normal development and regeneration, in cancer, and in evolution, by integrating cutting-edge experimental and computational technologies. His lab developed DNA methylomics technologies, algorithms to identify regulatory motifs and modules, and analytical and visualization tools to integrate large genomic and epigenomic data. His lab is home to the WashU Epigenome Browser, utilized by investigators around the world to access hundreds of thousands of genomic datasets generated by large Consortia including the NIH Roadmap Epigenome Project, ENCODE, 4D Nucleome, TaRGET, IGVF, and the Human Pangenome Project.
Dr. Wang currently directs the NIEHS Environmental Epigenomics Data Center, the Human Pangenome Reference Consortium, and the IGVF Data Administrative and Coordination Center.